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Intensity Modulated Radiation Therapy (IMRT)
IGRT and IMRT are the most technologically advanced treatments available in external beam radiation therapy. These enable the Maddock Center
to control the dose distribution to increase the radiation
delivered to the tumor while lowering the amount of radiation
to adjacent radiosensitive tissues.
There are essentially three components of a successful IMRT
treatment plan:
- Tighter Margins (as compared with either conventional or
3-dimensional treatment planning). Because IMRT uses more fields
and many field segments (beams) to shape the radiation to the
exact contours of the tumor, we can shrink the margin of normal
tissue affected by the radiation. This means that nearby normal
tissues receive a lower dose of radiation, which in turn means
fewer side effects.
- Dose Escalation. Because the margins of IMRT are so tightly
controlled, we can actually increase the dose delivered to the
tumor itself, thereby reducing the risk of local recurrence.
- Tumor localization. Accurate daily
set ups are particularly important when treating cancer of the
prostate. We use CT cone-beam imaging and/or real-time ultrasound localization to ensure the highest degree of accuracy during treatment.
For more information on IMRT and the technology and techniques
that make this advance in care feasible, please see Dr.
Maddock’s
recent article on IMRT in Medicine and Health, a publication
of the Rhode Island Medical Society.

Different field arrangements as defined by
the Multi Leaf Coordinator, a critical
component of IMRT therapy.
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Therapies & Technologies at
the Maddock Center:
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